Published Manuscripts


Lucky Sekhon, MD, Joseph A. Lee, BA, Eric Flisser, MD, Alan B. Copperman, MD, Daniel Stein, MD. Blastocyst vitrification, cryostorage and warming does not impact embryo transfer success, infant birthweight or timing of delivery.
Reproductive BioMedicine Online 2018

Nola S. Herlihy, Lucky Sekhon, Joseph A. Lee, Daniel Stein, Alan B. Copperman, Matthew A. Lederman. Caring for BRCA Carriers Strategies to Promote Health and Preserve Fertility
Journal of Women’s Health and Gynecology, March 08, 2018.


Carlos Hernandez-Nieto, M.D., Joseph Lee, B.A., Taraneh Nazem, M.D., Dmitry Gounko, M.A., Alan Copperman, M.D., and Benjamin Sandler, M.D. Embryo aneuploidy is not impacted by selective serotonin reuptake inhibitor exposure. Fertility and Sterility® Vol. 108, No. 6, December 2017.

Chloe Getrajdman, BA; Joseph A. Lee, BA; Alan B. Copperman, MD. Co-ivf for same-sex female couples Semin Reprod Med 2017;00:1–5.

Vela G, Ruman J, Luna M, Sandler B, and Copperman AB. Profound pituitary suppression following oral contraceptive pretreatment in gonadotropin-releasing hormone antagonist cycles does not impact outcome: a retrospective cohort study. JFIV Reprod Med Genet 2017, 5:2.

Ange Wang, M.D., Anthony Santistevan, M.S., Karen Hunter Cohn, Ph.D., Alan Copperman, M.D., John Nulsen, M.D., Brad T. Miller, M.D., Eric Widra, M.D., Lynn M. Westphal, M.D., Piraye Yurttas Beim, Ph.D. Freeze-only versus fresh embryo transfer in a multicenter matched cohort study: contribution of progesterone and maternal age to success rates. Fertil Steril 2017.

Etan Dayan, Hongfa Zhub, Alan B. Copperman, Sara Lewis, Amita Kamath. Gastrointestinal stromal tumor presenting as a right adnexal mass with histopathologic correlation. Clinical Imaging, 2017; 44 (2017) 97–100.

Lucky Sekhon, MD, Kathryn Shaia, MD, Anthony Santistevan MS, Karen Hunter Cohn PhD, Joseph A. Lee, BA, Piraye Yurttas Beim, PhD, Alan B. Copperman, MD. The cumulative dose of gonadotropins used for controlled ovarian stimulation does not influence the odds of embryonic aneuploidy in patients with normal ovarian response. JARG. March 2017 DOI 10.1007/s10815-017-0909-3.

Jorge Rodriguez-Purata, MD; Robert Pacheco, BA; Lucky Sekhon, MD; Joseph A. Lee, BA; Lawrence Grunfeld, MD; Tanmoy Mukherjee, MD; Benjamin Sandler, MD; Alan B. Copperman, MD. Reproductive outcome is optimized when an embryo transfer is performed 1 to 3 months after cervical dilation. J Gynec Obstet 2017; 1:004.

Luca Lambertini, Shira Rebecca Saul, Alan B. Copperman, Sara Salehi Hammerstad, Zhengzi Yi, Weijia Zhang, Yaron Tomer, and Nathan Kase Intrauterine Reprogramming of the Polycystic Ovary Syndrome Evidence from a Pilot Study of Cord Blood Global Methylation Analysis Front. Endocrinol., 18 December 2017.

Jorge Rodriguez-Purata, MD; Joseph Lee, BA; Michael Whitehouse, BA; Benjamin Sandler MD; Alan Copperman and Tanmoy Mukherjee, MD. Comparison of letrozole with timed intercourse versus clomiphene citrate with intrauterine insemination in patients with unexplained infertility. J Reprod Med. January Issue 2017.


Jorge Rodriguez-Purata, MD; Julian Gingold, MD, PhD; Joseph A. Lee, BA; Michael C. Whitehouse, BA; Richard Slifkin, BA; Christine Briton-Jones, PhD; Alan B. Copperman, MD; Benjamin Sandler, MD. Hatching status before embryo transfer is not correlated with implantation rate in chromosomally screened blastocysts. Hum Reprod. 2016 Sep 12.

Jorge Rodriguez-Purata, MD; Joseph Lee, BA; Michael Whitehouse, BA; Marlena Duke, MS; Lawrence Grunfeld, MD; Benjamin Sandler, MD; Alan Copperman, MD; Tanmoy Mukherjee, MD. Reproductive outcome is optimized by genomic embryo screening, vitrification and subsequent transfer into a prepared synchronous endometrium. J Assist Reprod Genet (2016) 33:401–412.


Rodriguez-Purata J, Lee J, Whitehouse M, Moschini RM, Knopman J, Duke M, Sandler B, Copperman A. Embryo selection versus natural selection - how do outcomes of comprehensive chromosome screening of blastocysts compare with the analysis of products of conception from early pregnancy loss (dilation and curettage)among an assisted reproductive technology population? Fertil Steril. 2015 Dec;104(6):1460-1466.

Gingold JA, Lee JA, Rodriguez-Purata J, Whitehouse MC, Sandler B, Grunfeld L, Mukherjee T, Copperman AB. Endometrial pattern, but not endometrial thickness, affects implantation rates in euploid embryo transfers. Fertil Steril. 2015 Sep;104(3):620-8.

Gingold JA, Lee JA, Whitehouse MC, Rodriguez-Purata J, Sandler B, Grunfeld L, Mukherjee T, Copperman AB. Maximum basal FSH predicts reproductive outcome better than cycle-specific basal FSH levels: waiting for a “better” month conveys limited retrieval benefits. Reprod Biol Endocrinol. 2015 Aug 15;13:91.


Arielle Yeshua, Joseph A. Lee, Georgia Witkin, Alan B. Copperman. Female Couples Undergoing IVF with Partner Eggs (Co-IVF): Pathways to Parenthood. LGBT Health. June 2015, 2(2): 135-139.

Lee JA, Sekhon L, Grunfeld L, Copperman AB. In-vitro maturation of germinal vesicle and metaphase I eggs prior to cryopreservation optimizes reproductive potential in patients undergoing fertility preservation. Curr Opin Obstet Gynecol. 2014 Jun;26(3):168-73.

Flores H, Lee J, Rodriguez-Purata J, Witkin G, Sandler B, Copperman AB. Beauty, brains or health: trends in ovum recipient preferences. J Womens Health (Larchmt). 2014 Oct;23(10):830-3.

VanWort TA, Lee JA, Karvir H, Whitehouse MC, Beim PY, Copperman AB. Female cystic fibrosis mutation carriers and assisted reproductive technology: does carrier status affect reproductive outcomes? Fertil Steril. 2014 Nov;102(5):1324-30.

Werner MD, Leondires MP, Schoolcraft WB, Miller BT, Copperman AB, Robins ED, Arredondo F, Hickman TN, Gutmann J, Schillings WJ, Levy B, Taylor D, Treff NR, Scott RT Jr. Clinically recognizable error rate after the transfer of comprehensive chromosomal screened euploid embryos is low. Fertil Steril. 2014 Dec;102(6):1613-8.


Victoria Vallejo, Joseph A. Lee, Lisa Schuman, Georgia Witkin, Enrique Cervantes, Benjamin Sandler, Alan B. Copperman. Social and psychological assessment of women undergoing elective oocyte cryopreservation - A 7-year analysis. Open Journal of Obstetrics and Gynecology, 2013, 3, 1-7.

Luna M, Vela G, McDonald CA, Copperman AB. Results with GnRH antagonist protocols are equivalent to GnRH agonist protocols in comparable patient populations. J Reprod Med. 2012 Mar-Apr;57(3-4):123-8.

Victoria Vallejo, Hilde I.G. Cotton, Joseph A. Lee, Enrique Cervantes, Benjamin Sandler M.D, Alan B Copperman. Medical versus surgical treatment for early pregnancy loss in infertile patients - Which approach facilitates more rapid return to subsequent treatment cycle? OJOG November 2012: Vol.2 No.4; ISSN #: 2160-8792.

Casey A. McDonald, Zachary A. Haimowitz, Andrea DeVenuta, Charity Reeves, Alan B. Copperman, Jason Barritt. Replacing liquid fyrite with digital to improve in vitro fertilization laboratory quality control procedures. Open Journal of Obstetrics and Gynecology, 2012, 2.


Gerardo Vela, M.D., Martha Luna, M.D., Jason Barritt, Ph.D., Benjamin Sandler, M.D., Alan B. Copperman, M.D. Monozygotic pregnancies conceived by in vitro fertilization - understanding their prognosis. Fertil Steril 2011;95:606–10.

Izadyar F, Wong J, Maki C, Pacchiarotti J, Ramos T, Howerton K, Yuen C, Greilach S, Zhao HH, Chow M, Chow YC, Rao J, Barritt J, Bar-Chama N, Copperman AB. Identification and characterization of repopulating spermatogonial stem cells from the adult human testis. Hum Reprod. 2011 Jun;26(6):1296-306

Moschini RM, Chuang L, Poleshchuk F, Slifkin RE, Copperman AB, Barritt J. Commercially available enhanced in vitro maturation medium does not improve maturation of germinal vesicle and metaphase I oocytes in standard in vitro fertilization cases. Fertil Steril. 2011 Jun 30;95(8):2645-7.

McDonald CA, Valluzo L, Chuang L, Poleshchuk F, Copperman AB, Barritt J. Nitrogen vapor shipment of vitrified oocytes - time for caution. Fertil Steril. 2011 Jun 30;95(8):2628-30.

Grunfeld L, Sandler B, Mukherjee T, Copperman AB. (Case Report) Parental karyotype may reveal the source of a pregnancy loss even in the presence of a reportedly euploid fetal karyotype. Fertil Steril. 2011 Mar 1;95(3):1120

Luna M, Bigelow C, Duke M, Ruman J, Sandler B, Grunfeld L, Copperman AB. Should ICSI be recommended routinely in patients with four or fewer oocytes retrieved? J Assist Reprod Genet. 2011 Sep;28(10):911-5

2010 & Prior

Eliyahu E, Shtraizent N, Martinuzzi K, Barritt J, He X, Wei H, Chaubal S, Copperman AB, Schuchman EH. Acid ceramidase improves the quality of oocytes and embryos and the outcome of in vitro fertilization. FASEB J. 2010 Apr;24(4):1229-38

Flisser E, Copperman AB. Why do couples drop-out from IVF treatment? Hum Reprod. 2009 Mar;24(3):758-9

Luna M, Finkler E, Barritt J, Bar-Chama N, Sandler B, Copperman AB, Grunfeld L. Paternal age and assisted reproductive technology outcome in ovum recipients. Fertil Steril. 2009 Nov;92(5):1772-5

Knopman J, Copperman AB. (Letter to Editor) Endometrial thickness measured by ultrasound scan in women with uterine outlet obstruction due to intrauterine or upper cervical adhesions. Hum Reprod. 2008 May;23(5):1234

Luna M, Copperman AB, Duke M, Ezcurra D, Sandler B, Barritt J. Human blastocyst morphological quality is significantly improved in embryos classified as fast on day 3 (>or=10 cells), bringing into question current embryological dogma. Fertil Steril. 2008 Feb;89(2):358-63.

Grunfeld L, Luna M, Mukherjee T, Sandler B, Nagashima Y, Copperman AB. Redefining in vitro fertilization success: should triplets be considered failures? Fertil Steril. 2008 Oct;90(4):1064-8.

Martinuzzi K, Ryan S, Luna M, Copperman AB. Elevated body mass index (BMI) does not adversely affect in vitro fertilization outcome in young women. J Assist Reprod Genet. 2008 May;25(5):169-75.

Flisser E, Scott RT Jr, Copperman AB. (Editor’s Corner) Patient-friendly IVF: how should it be defined? Fertil Steril. 2007 Sep;88(3):547-9.

Martha Luna, M.D., Marlena Duke, M.Sc., Alan Copperman, Lawrence Grunfeld, M.D., Benjamin Sandler, M.D., and Jason Barritt, Ph.D. Blastocyst embryo transfer is associated with a sex-ratio imbalance in favor of male offspring. Fertil Steril 2007;87:519 –23.

Copperman KB, Schertz JC, Witkin G, Sandler B, Brodman M, Copperman AB. Patients’ return to referring physicians and its relation to their infertility duration. J Womens Health (Larchmt). 2007 Sep;16(7):1012-6.

Schiff JD1, Luna M, Barritt J, Duke M, Copperman A, Bar-Chama N. The morphology of extracted testicular sperm correlates with fertilization but not pregnancy rates. BJU Int. 2007 Dec;100(6):1326-9.

Barritt J, Luna M, Duke M, Grunfeld L, Mukherjee T, Sandler B, Copperman AB. Report of four donor-recipient oocyte cryopreservation cycles resulting in high pregnancy and implantation rates. Fertil Steril. 2007 Jan;87(1):189.

Barritt J, Luna M, Duke M, Copperman A. (Letter to Editor) Ethical issues surrounding the cryopreservation of human oocytes. Fertil Steril. 2007 Oct;88(4):1016.

Barritt J, Luna M, Duke M, Copperman A. (Letter to Editor) Perspectives on oocyte research. Fertil Steril. 2007 Oct;88(4):1019-20.

Knopman J, Copperman AB. Value of 3D ultrasound in the management of suspected Asherman’s syndrome. J Reprod Med. 2007 Nov;52(11):1016-22.

Alan B. Copperman, M.D.,a and Alan H. DeCherney, M.D.b. Turn, Turn, Turn. Fertil Steril 2006;85:12–3.

Kliman HJ, Honig S, Walls D, Luna M, McSweet JC, Copperman AB. Optimization of endometrial preparation results in a normal endometrial function test (EFT) and good reproductive outcome in donor ovum recipients. J Assist Reprod Genet. 2006 Jul-Aug;23(7-8):299-303.

Copperman AB, Wells V, Luna M, Kalir T, Sandler B, Mukherjee T. Presence of hydrosalpinx correlated to endometrial inflammatory response in vivo. Fertil Steril. 2006 Oct;86(4):972-6.

Alan B. Copperman, M.D. Antagonists in poor-responder patients. FERTILITY AND STERILITY VOL. 80, SUPPL. 1, JULY 2003

Babinszki A, Mukherjee T, Kerenyi T, Berkowitz RL, Copperman AB. Diagnosing amnionicity at 6 weeks of pregnancy with transvaginal three-dimensional ultrasonography: case report. Fertil Steril 1999; 71:1161-4.

Chen HL, Copperman AB, Grunfeld L, Sandler B, Bustillo M, Gordon JW. Failed fertilization in vitro: second day micromanipulation of oocytes versus reinsemination. Fertil Steril 1995; 63:1337-40.

Copperman AB, DeCherney AH, Olive DL. A case of endometrial cancer following endometrial ablation for dysfunctional uterine bleeding. Obstet Gynecol 1993; 82:640-2.

Copperman AB, Bustillo M. Biochemical and sonographic evaluation of the very early intrauterine pregnancy. Early Pregnancy 1995; 1:106-18.

Copperman AB, Kaltenbacher L, Walker B, Sandler B, Bustillo M, Grunfeld L. Early first-trimester ultrasound provides a window through which the chorionicity of twins can be diagnosed in an in vitro fertilization (IVF) population. J Assist Reprod Genet 1995; 12:693-7.

Copperman AB, Selick CE, Grunfeld L, Sandler B, Bustillo M. Cumulative number and morphological score of embryos resulting in success: realistic expectations from in vitro fertilization-embryo transfer. Fertil Steril 1995; 64:88-92.

Copperman AB, Horowitz GM, Kaplan P, Scott RT, Navot D, Hofmann GE. Relationship between circulating human chorionic gonadotropin levels and premature luteinization in cycles of controlled ovarian hyperstimulation. Fertil Steril 1995; 63:1267-71.

Copperman AB, Mukherjee T, Grunfeld L, Sandler B, Bustillo M. Ovarian hyperstimulation syndrome complicated by uterine prolapse. J Assist Reprod Genet 1995; 12:343-5.

Copperman SM, Copperman AB, Safford BH, South-Paul JE. Four happy doctors: what’s their secret?. Interview by Neil Chesanow. Med Econ 1999; 76:218-20.

Dunn TM, Grunfeld L, Kardon NB. Trisomy 1 in a clinically recognized IVF pregnancy. Am J Med Genet 2001; 99:152-3.

Fleischer A, Schulman H, Farmakides G, et al. Uterine artery Doppler velocimetry in pregnant women with hypertension. Am J Obstet Gynecol 1986; 154:806-13.

Friedman F, Jr., Copperman AB, Brodman ML, Shah D, Sandler B, Grunfeld L. Perinatal outcome after embryo transfer in ovum recipients. A comparison with standard in vitro fertilization. J Reprod Med 1996; 41:640-4.

Garrisi GJ, Talansky BE, Grunfeld L, Sapira V, Navot D, Gordon JW. Clinical evaluation of three approaches to micromanipulation-assisted fertilization. Fertil Steril 1990; 54:671-7.

Gordon JW, Grunfeld L, Garrisi GJ, Talansky BE, Richards C, Laufer N. Fertilization of human oocytes by sperm from infertile males after zona pellucida drilling. Fertil Steril 1988; 50:68-73.

Gordon JW, Grunfeld L, Garrisi GJ, Navot D, Laufer N. Successful microsurgical removal of a pronucleus from tripronuclear human zygotes. Fertil Steril 1989; 52:367-72.

Grunfeld L. Current trends in mammography. Mt Sinai J Med 1979; 46:341-3.

Grunfeld L, Sandler B, Fox J, Boyd C, Kaplan P, Navot D. Luteal phase deficiency after completely normal follicular and periovulatory phases. Fertil Steril 1989; 52:919-23.

Grunfeld L. Workup for male infertility. J Reprod Med 1989; 34:143-9.

Grunfeld L, Walker B, Bergh PA, Sandler B, Hofmann G, Navot D. High-resolution endovaginal ultrasonography of the endometrium: a noninvasive test for endometrial adequacy. Obstet Gynecol 1991; 78:200-4.

Grunfeld L, Sandler B, Fox JH, Williams M, Navot D. Ovarian hyperstimulation and follicular aspiration. Effect on ovulatory function. J Reprod Med 1992; 37:227-31.

Grunfeld L. The uterus and endometrium. Clin Obstet Gynecol 1996; 39:175-87.

Lavy G, Restrepo-Candelo H, Diamond M, Shapiro B, Grunfeld L, DeCherney AH. Laparoscopic and transvaginal ova recovery: the effect on ova quality. Fertil Steril 1988; 49:1002-6.

Levy B, Mukherjee T, Hirschhorn K. Molecular cytogenetic analysis of uterine leiomyoma and leiomyosarcoma by comparative genomic hybridization. Cancer Genet Cytogenet 2000; 121:1-8.

Lih CH, Grunfeld L, Sandler B, Drews MR, Navot D, Gordon JW. Infertile couples with normal counts who require subzonal sperm insertion possess a fertility defect that affects zona pellucida penetration. Hum Reprod 1994; 9:2335-8.

Marcus M, Grunfeld L, Berkowitz G, Kaplan P, Godbold J. Urinary follicle-stimulating hormone as a biological marker of ovarian toxicity. Fertil Steril 1993; 59:931-3.

Mukherjee T, Copperman AB, Sandler B, Bustillo M, Grunfeld L. Severe ovarian hyperstimulation despite prophylactic albumin at the time of oocyte retrieval for in vitro fertilization and embryo transfer. Fertil Steril 1995; 64:641-3.

Mukherjee T, Copperman AB, McCaffrey C, Cook CA, Bustillo M, Obasaju MF. Hydrosalpinx fluid has embryotoxic effects on murine embryogenesis: a case for prophylactic salpingectomy. Fertil Steril 1996; 66:851-3.

Mukherjee T, Copperman AB, Grunfeld L, Bustillo M. Albumin for ovarian hyperstimulation? Fertil Steril 1996; 66:173-4.

Mukherjee T, Copperman AB, Lapinski R, Sandler B, Bustillo M, Grunfeld L. An elevated day three follicle-stimulating hormone:luteinizing hormone ratio (FSH:LH) in the presence of a normal day 3 FSH predicts a poor response to controlled ovarian hyperstimulation. Fertil Steril 1996; 65:588-93.

Nait-Oumesmar B, Copperman AB, Lazzarini RA. Placental expression and chromosomal localization of the human Gcm 1 gene. J Histochem Cytochem 2000; 48:915-22.

Nasseri A, Mukherjee T, Grifo JA, Noyes N, Krey L, Copperman AB. Elevated day 3 serum follicle stimulating hormone and/or estradiol may predict fetal aneuploidy. Fertil Steril 1999; 71:715-8.

Navot D, Bergh PA, Williams MA, et al. Poor oocyte quality rather than implantation failure as a cause of age-related decline in female fertility. Lancet 1991; 337:1375-7.

Navot D, Bergh PA, Williams M, et al. An insight into early reproductive processes through the in vivo model of ovum donation. J Clin Endocrinol Metab 1991; 72:408-14.

Rosenblatt MA, Bradford CN, Bodian CA, Grunfeld L. The effect of a propofol-based sedation technique on cumulative embryo scores, clinical pregnancy rates, and implantation rates in patients undergoing embryo transfers with donor oocytes. J Clin Anesth 1997; 9:614-7.

Schulman H, Fleischer A, Farmakides G, Bracero L, Rochelson B, Grunfeld L. Development of uterine artery compliance in pregnancy as detected by Doppler ultrasound. Am J Obstet Gynecol 1986; 155:1031-6.

Selick CE, Hofmann GE, Albano C, et al. Embryo quality and pregnancy potential of fresh compared with frozen embryos–is freezing detrimental to high quality embryos? Hum Reprod 1995; 10:392-5.

Stadtmauer L, Grunfeld L. The significance of endometrial filling defects detected on routine transvaginal sonography. J Ultrasound Med 1995; 14:169-72; discussion 173-4.

Sung L, Bustillo M, Mukherjee T, Booth G, Karstaedt A, Copperman AB. Sisters of women with premature ovarian failure may not be ideal ovum donors. Fertil Steril 1997; 67:912-6.

Sung L, Mukherjee T, Takeshige T, Bustillo M, Copperman AB. Endometriosis is not detrimental to embryo implantation in oocyte recipients. J Assist Reprod Genet 1997; 14:152-6.

Vazquez-Levin M, Kaplan P, Guzman I, Grunfeld L, Garrisi GJ, Navot D. The effect of female antisperm antibodies on in vitro fertilization, early embryonic development, and pregnancy outcome. Fertil Steril 1991; 56:84-8.

Viscarello RR, Copperman AB, DeGennaro NJ. Is the risk of perinatal transmission of human immunodeficiency virus increased by the intrapartum use of spiral electrodes or fetal scalp pH sampling? Am J Obstet Gynecol 1994; 170:740-3

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